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Adenomyosis & Prolactin: Break Free From the Pain

picture of a seated woman holding an orchid. She is thinking about the connection between adenomyosis and prolactin
Abdominal pain may be from adenomyosis
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Natural Treatment for Adenomyosis

Reading and researching are constants for a naturopathic doctor. This week, while reviewing some research regarding adenomyosis, I came across an older study that I thought was interesting.

Firstly, what is adenomyosis?

This condition involves uterine lining tissue that has infiltrated the muscular wall of your uterus.  This tissue responds to changes in hormone levels throughout your monthly menstrual cycle.  This creates pelvic pain and menstrual cramps and contributes to infertility.

Back to the study I mentioned.  It used a mouse model to increase blood levels of the hormone prolactin.  By increasing prolactin, the investigators could rapidly and frequently cause uterine adenomyosis.

Prolactin isn’t the only game in town where adenomyosis is concerned.  Other hormones associated with adenomyosis include estrogen, FSH, and progesterone.

What is Prolactin?

Prolactin is a hormone secreted from a gland in your brain known as your pituitary gland.  Women make this hormone to facilitate breastfeeding.  However, prolactin levels can be increased even when you are not breastfeeding.  

What Increases Prolactin?

Aside from while you are breastfeeding, prolactin increases when you are under stress.  It also goes up if you have a prolactin-secreting tumour in your pituitary.  This is called a prolactinoma.  Identifying a prolactinoma requires MRI imaging.

How can you test prolactin?

Measuring prolactin involves a simple blood test.

How can you reduce prolactin?

Lowering prolactin depends on why it is high.  If you are breastfeeding, it will naturally be high, and we don’t want to reduce it in this case.  Otherwise, the herb Chaste tree (Vitex Agnus-Castus) helps to lower prolactin.  Supporting healthy dopamine production through vitamin B6, magnesium, and the amino acid tyrosine also helps to lower prolactin.  Stress reduction is important if stress is the cause of high prolactin.  If stress is the issue, supporting your HPA axis (adrenal glands) helps you handle stress better, lowering the production of stress-related prolactin.

Hormones and Adenomyosis

Other hormones that cause or contribute to adenomyosis can also be balanced through natural means, such as diet, exercise, stress reduction, support of the endocrine system, and herbs like Chastetree. I can help. 

In summary, elevated prolactin levels (hyperprolactinemia) have been associated with the development and progression of adenomyosis, a condition where endometrial tissue grows into the muscular wall of the uterus. High prolactin may disrupt normal hormonal signalling, contributing to abnormal uterine tissue growth, inflammation, and pain. This hormonal imbalance can worsen menstrual symptoms, including heavy bleeding and cramping.

Naturopathic treatment addresses the root causes of hormone imbalances by supporting the body’s natural healing processes. A naturopathic doctor can help regulate prolactin levels, reduce inflammation, and improve overall hormone function through dietary adjustments, stress management, herbal medicine, and targeted nutritional supplements. This holistic approach may help relieve symptoms, reduce the progression of adenomyosis, and improve quality of life by considering the whole person—not just the diagnosis. Naturopathic care offers a gentle, individualized path to hormone balance and uterine health.

Medically reviewed by Dr Pamela Frank, BSc(Hons), ND, updated April 24, 2025

I do not recommend self-medicating.  For help specific to your situation, book an appointment by calling 416-481-0222 or book online here.


Dr. Pamela Frank has been in practice as a naturopathic doctor for over 26 years. Since 1999, she has earned acclaim as a leading naturopath in Toronto, amassing multiple awards.

Dr. Pamela has a special interest in addressing hormone-related complexities, including but not limited to PCOS, endometriosis, acne, hair loss, weight management, thyroid issues, and fertility.

Residing in Toronto with her family and loyal companion, Dolly the rescue dog, Dr. Pamela seamlessly combines her professional commitment with a diverse range of interests.

Beyond her clinical endeavours, she actively engages in kickboxing, leadership roles within Scout Groups, yoga practice, podcasting, and outdoor pursuits such as backcountry camping.

Dr. Pamela’s comprehensive approach reflects not only her dedication to optimal health but also her passion for continual personal and professional growth.

Dr. Pamela Frank, BSc(Hons), ND

Dr. Pamela Frank, BSc(Hons), ND

Dr. Pamela Frank, has been in practice as a naturopathic doctor for more than 26 years. She has earned acclaim as a leading naturopath in Toronto since 1999, amassing multiple awards. Dr. Pamela has a special interest in addressing hormone-related complexities, including but not limited to PCOS, endometriosis, acne, hair loss, weight management, thyroid issues, and fertility. Residing in Toronto with her family and loyal companion, Dolly the rescue dog, Dr. Pamela seamlessly combines her professional commitment with a diverse range of interests. Beyond her clinical endeavours, she actively engages in kickboxing, leadership roles within Scout Groups, yoga practice, podcasting, and outdoor pursuits such as backcountry camping. Dr. Pamela's comprehensive approach reflects not only her dedication to optimal health but also her passion for continual personal and professional growth. Check out my LinkedIn Profile .